In recent decades, particularly acute problem of osteoporosis, its prevalence, due to an aging population, growth, improving capacities of diagnosis, the negative impact on the duration and quality of life, etc. [1, 9, 13, 43].

Osteoporosis - a disease that is accompanied by reduced bone strength due to the decrease in bone density and changes in its structure, leading to an increase in its brittleness.

Following the introduction of technologies for the synthesis and industrial production of penicillin in the 40s., Began the "golden era" in the development of chemotherapy, accompanied by the discovery and development of new classes and groups of antimicrobial agents.

nfektsii upper respiratory tract infections (URI) took first place in the structure of morbidity and account for 70%. According to WHO, each year ARI is sick, every third inhabitant of the planet. Among the complications of acute respiratory infections sinusitis leading place, followed by otitis and tonzillofaringity.

Cefuroxime aksetil - bactericidal beta-lactam antibiotic belonging to the group of second-generation cephalosporins. It pronounced activity against microorganisms of the family Enterobacteriaceae, Haemophilus influenzae and Moraxella catarrhalis (with comparable activity against Gram-positive cocci). This is due to the fact that cefuroxime is highly resistant to beta-lactamase produced by gram-negative pathogens.